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Select item 88195151.

Advances in the Development and the Applications of Nonviral, Episomal Vectors for Gene Therapy

Grace Elizabeth Mulia, Virginia Picanço-Castro, Eleana F. Stavrou, Aglaia Athanassiadou, Marxa Leão Figueiredo

Hum Gene Ther. October 2021; 32(19-20): 1076–1095. Published online 2021 Oct 18. doi: 10.1089/hum.2020.310

PMCID:: PMC8819515

Article PDF–1.1M

Select item 104851202.

Production of retroviral vectors in continuous high cell density culture

Marc D. Hein, Daniel Kazenmaier, Yasemin van Heuvel, Tanya Dogra, Maurizio Cattaneo, Sascha Y. Kupke, Jörn Stitz, Yvonne Genzel, Udo Reichl

Appl Microbiol Biotechnol. 2023; 107(19): 5947–5961. Published online 2023 Aug 5. doi: 10.1007/s00253-023-12689-9

PMCID:: PMC10485120

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Select item 58652563.

Adenoviral Type 35 and 26 Vectors with a Bidirectional Expression Cassette in the E1 Region Show an Improved Genetic Stability Profile and Potent Transgene-Specific Immune Response

Marija Vujadinovic, Kerstin Wunderlich, Benoit Callendret, Marina Koning, Mark Vermeulen, Barbara Sanders, Esmeralda van der Helm, Adile Gecgel, Dirk Spek, Karin de Boer, Masha Stalknecht, Jan Serroyen, Maria Grazia Pau, Hanneke Schuitemaker, Roland Zahn, Jerome Custers, Jort Vellinga

Hum Gene Ther. 2018 Mar 1; 29(3): 337–351. Published online 2018 Mar 1. doi: 10.1089/hum.2017.023

PMCID:: PMC5865256

Article PDF–811K

Select item 79161224.

Lentiviral Vector Bioprocessing

Christopher Perry, Andrea C. M. E. Rayat

Viruses. 2021 Feb; 13(2): 268. Published online 2021 Feb 9. doi: 10.3390/v13020268

PMCID:: PMC7916122

Article PDF–1004K

Select item 60150335.

A uniform cloning platform for mycobacterial genetics and protein production

Fabian M. Arnold, Michael Hohl, Sille Remm, Hendrik Koliwer-Brandl, Sophia Adenau, Sasitorn Chusri, Peter Sander, Hubert Hilbi, Markus A. Seeger

Sci Rep. 2018; 8: 9539. Published online 2018 Jun 22. doi: 10.1038/s41598-018-27687-5

PMCID:: PMC6015033

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Select item 53789766.

Enhancing titres of therapeutic viral vectors using the transgene repression in vector production (TRiP) system

H. E. Maunder, J. Wright, B. R. Kolli, C. R. Vieira, T. T. Mkandawire, S. Tatoris, V. Kennedy, S. Iqball, G. Devarajan, S. Ellis, Y. Lad, N. G. Clarkson, K. A. Mitrophanous, D. C. Farley

Nat Commun. 2017; 8: 14834. Published online 2017 Mar 27. doi: 10.1038/ncomms14834

PMCID:: PMC5378976

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Select item 78686767.

Viral vector platforms within the gene therapy landscape

Jote T. Bulcha, Yi Wang, Hong Ma, Phillip W. L. Tai, Guangping Gao

Signal Transduct Target Ther. 2021; 6: 53. Published online 2021 Feb 8. doi: 10.1038/s41392-021-00487-6

PMCID:: PMC7868676

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Select item 64783818.

Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization.

Peirong Hu, Yanmin Bi, Hong Ma, Thipparat Suwanmanee, Brian Zeithaml, Nate J. Fry, Donald B. Kohn, Tal Kafri

Gene Ther. Author manuscript; available in PMC 2019 Apr 23.

Published in final edited form as: Gene Ther. 2018 Oct; 25(7): 454–472. Published online 2018 Sep 6. doi: 10.1038/s41434-018-0039-2

PMCID:: PMC6478381

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Select item 51131059.

Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression

Xiaoou Jiang, Han Yu, Cui Rong Teo, Genim Siu Xian Tan, Sok Chin Goh, Parasvi Patel, Yiqiang Kevin Chua, Nasirah Banu Sahul Hameed, Antonio Bertoletti, Volker Patzel

Mol Ther. 2016 Sep; 24(9): 1581–1591. Prepublished online 2016 Jun 30. Published online 2016 Aug 2. doi: 10.1038/mt.2016.138

PMCID:: PMC5113105

Article PDF–943K

Select item 1009078210.

Evolutionary consequences of vector-borne transmission: how using vectors shapes host, vector and pathogen evolution

Daniela de Angeli Dutra, Robert Poulin, Francisco C. Ferreira

Parasitology. 2022 Nov; 149(13): 1667–1678. Published online 2022 Oct 6. doi: 10.1017/S0031182022001378

PMCID:: PMC10090782

Article PDF–494K

Select item 890562711.

An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes

Lieve E. H. van der Donk, Jet van der Spek, Tom van Duivenvoorde, Marieke S. ten Brink, Teunis B. H. Geijtenbeek, Coenraad P. Kuijl, Jeroen W. J. van Heijst, Louis S. Ates

Biol Open. 2022 Feb 15; 11(2): bio059032. Published online 2022 Mar 1. doi: 10.1242/bio.059032

PMCID:: PMC8905627

Article PDF–3.5M

Select item 565836512.

Bacillus SEVA siblings: A Golden Gate-based toolbox to create personalized integrative vectors for Bacillus subtilis

Jara Radeck, Daniel Meyer, Nina Lautenschläger, Thorsten Mascher

Sci Rep. 2017; 7: 14134. Published online 2017 Oct 26. doi: 10.1038/s41598-017-14329-5

Correction in:: Sci Rep. 2018; 8: 1306.

Correction in:: Sci Rep. 2018; 8: 4297.

PMCID:: PMC5658365

Article PDF–2.6M

Select item 548826013.

Adeno-Associated Virus Vectors and Stem Cells: Friends or Foes?

Nolan Brown, Liujiang Song, Nageswara R. Kollu, Matthew L. Hirsch

Hum Gene Ther. 2017 Jun 1; 28(6): 450–463. Published online 2017 Jun 1. doi: 10.1089/hum.2017.038

PMCID:: PMC5488260

Article PDF–371K

Select item 940721314.

Appraisal for the Potential of Viral and Nonviral Vectors in Gene Therapy: A Review

Muhammad Hammad Butt, Muhammad Zaman, Abrar Ahmad, Rahima Khan, Tauqeer Hussain Mallhi, Mohammad Mehedi Hasan, Yusra Habib Khan, Sara Hafeez, Ehab El Sayed Massoud, Md. Habibur Rahman, Simona Cavalu

Genes (Basel) 2022 Aug; 13(8): 1370. Published online 2022 Jul 30. doi: 10.3390/genes13081370

PMCID:: PMC9407213

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Select item 1040986515.

A mosaic adeno-associated virus vector as a versatile tool that exhibits high levels of transgene expression and neuron specificity in primate brain

Kei Kimura, Yuji Nagai, Gaku Hatanaka, Yang Fang, Soshi Tanabe, Andi Zheng, Maki Fujiwara, Mayuko Nakano, Yukiko Hori, Ryosuke F. Takeuchi, Mikio Inagaki, Takafumi Minamimoto, Ichiro Fujita, Ken-ichi Inoue, Masahiko Takada

Nat Commun. 2023; 14: 4762. Published online 2023 Aug 8. doi: 10.1038/s41467-023-40436-1

PMCID:: PMC10409865

Article PDF–6.6M

Select item 583511616.

Triple Vectors Expand AAV Transfer Capacity in the Retina

Andrea Maddalena, Patrizia Tornabene, Paola Tiberi, Renato Minopoli, Anna Manfredi, Margherita Mutarelli, Settimio Rossi, Francesca Simonelli, Jurgen K. Naggert, Davide Cacchiarelli, Alberto Auricchio

Mol Ther. 2018 Feb 7; 26(2): 524–541. Published online 2017 Dec 5. doi: 10.1016/j.ymthe.2017.11.019

PMCID:: PMC5835116

Article PDF–2.8M

Select item 592916717.

Viral vectors for therapy of neurologic diseases

Sourav R. Choudhury, Eloise Hudry, Casey A. Maguire, Miguel Sena-Esteves, Xandra O. Breakefield, Paola Grandi

Neuropharmacology. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Neuropharmacology. 2017 Jul 1; 120: 63–80. Published online 2016 Feb 21. doi: 10.1016/j.neuropharm.2016.02.013

PMCID:: PMC5929167

Article PDF–979K

Select item 986747418.

High-Level rAAV Vector Production by rAdV-Mediated Amplification of Small Amounts of Input Vector

Stefan Weger

Viruses. 2023 Jan; 15(1): 64. Published online 2022 Dec 24. doi: 10.3390/v15010064

PMCID:: PMC9867474

Article PDF–6.2M

Select item 789770419.

β-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production

Jiaying Han, Kevin Tam, Feiyang Ma, Curtis Tam, Bamidele Aleshe, Xiaoyan Wang, Jason P. Quintos, Marco Morselli, Matteo Pellegrini, Roger P. Hollis, Donald B. Kohn

Stem Cell Reports. 2021 Jan 12; 16(1): 198–211. Published online 2020 Nov 12. doi: 10.1016/j.stemcr.2020.10.007